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Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin-Induces Cell Cycle Arrest in a Glycogen Synthase Kinase (GSK)-3-Dependent Manner in Oral Keratinocytes

Cytolethal distending toxins (Cdt) are produced by a diverse group of pathogens. One Cdt-producing organism, Aggregatibacter actinomycetemcomitans, plays a critical role in the pathogenesis of a unique form of periodontitis, formerly referred to as localized aggressive periodontitis. The active Cdt...

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Detalles Bibliográficos
Autores principales: Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Korostoff, Jonathon, Boesze-Battaglia, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570058/
https://www.ncbi.nlm.nih.gov/pubmed/36233133
http://dx.doi.org/10.3390/ijms231911831