FBP1-Altered Carbohydrate Metabolism Reduces Leukemic Viability through Activating P53 and Modulating the Mitochondrial Quality Control System In Vitro

Acute myeloid leukemia (AML)—the most frequent form of adult blood cancer—is characterized by heterogeneous mechanisms and disease progression. Developing an effective therapeutic strategy that targets metabolic homeostasis and energy production in immature leukemic cells (blasts) is essential for o...

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Detalles Bibliográficos
Autores principales: Xu, Yi, Tran, Lily, Tang, Janet, Nguyen, Vinh, Sewell, Elisabeth, Xiao, Jeffrey, Hino, Christopher, Wasnik, Samiksha, Francis-Boyle, Olivia L., Zhang, Ke K., Xie, Linglin, Zhong, Jiang F., Baylink, David J., Chen, Chien-Shing, Reeves, Mark E., Cao, Huynh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570078/
https://www.ncbi.nlm.nih.gov/pubmed/36232688
http://dx.doi.org/10.3390/ijms231911387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570078/
https://www.ncbi.nlm.nih.gov/pubmed/36232688
http://dx.doi.org/10.3390/ijms231911387

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