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FBP1-Altered Carbohydrate Metabolism Reduces Leukemic Viability through Activating P53 and Modulating the Mitochondrial Quality Control System In Vitro
Acute myeloid leukemia (AML)—the most frequent form of adult blood cancer—is characterized by heterogeneous mechanisms and disease progression. Developing an effective therapeutic strategy that targets metabolic homeostasis and energy production in immature leukemic cells (blasts) is essential for o...
Autores principales: | Xu, Yi, Tran, Lily, Tang, Janet, Nguyen, Vinh, Sewell, Elisabeth, Xiao, Jeffrey, Hino, Christopher, Wasnik, Samiksha, Francis-Boyle, Olivia L., Zhang, Ke K., Xie, Linglin, Zhong, Jiang F., Baylink, David J., Chen, Chien-Shing, Reeves, Mark E., Cao, Huynh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570078/ https://www.ncbi.nlm.nih.gov/pubmed/36232688 http://dx.doi.org/10.3390/ijms231911387 |
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