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Molecular Mechanisms Underlying Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase Signal Transduction

Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) is the activating kinase for multiple downstream kinases, including CaM-kinase I (CaMKI), CaM-kinase IV (CaMKIV), protein kinase B (PKB/Akt), and 5′AMP-kinase (AMPK), through the phosphorylation of their activation-loop Thr residues in respon...

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Detalles Bibliográficos
Autores principales: Tokumitsu, Hiroshi, Sakagami, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570080/
https://www.ncbi.nlm.nih.gov/pubmed/36232320
http://dx.doi.org/10.3390/ijms231911025