Dp71 Point Mutations Induce Protein Aggregation, Loss of Nuclear Lamina Integrity and Impaired Braf35 and Ibraf Function in Neuronal Cells

Dystrophin Dp71 is the most abundant product of the Duchenne muscular dystrophy gene in the nervous system, and mutations impairing its function have been associated with the neurodevelopmental symptoms present in a third of DMD patients. Dp71 is required for the clustering of neurotransmitter recep...

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Detalles Bibliográficos
Autores principales: Rugerio-Martínez, Claudia Ivette, Ramos, Daniel, Segura-Olvera, Abel, Murillo-Melo, Nadia Mireya, Tapia-Guerrero, Yessica Sarai, Argüello-García, Raúl, Leyva-García, Norberto, Hernández-Hernández, Oscar, Cisneros, Bulmaro, Suárez-Sánchez, Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570083/
https://www.ncbi.nlm.nih.gov/pubmed/36233175
http://dx.doi.org/10.3390/ijms231911876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570083/
https://www.ncbi.nlm.nih.gov/pubmed/36233175
http://dx.doi.org/10.3390/ijms231911876

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