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Platelet SR-PSOX/CXCL16–CXCR6 Axis Influences Thrombotic Propensity and Prognosis in Coronary Artery Disease

Platelets express the transmembrane chemokine SR-PSOX/CXCL16, proteolytic cleavage of which generates the sCXCL16 soluble-(s) chemokine. The sCXCL16 engages CXCR6 on platelets to synergistically propagate degranulation, aggregation and thrombotic response. Currently, we have investigated the pro-thr...

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Detalles Bibliográficos
Autores principales: Guan, Tianyun, Emschermann, Frederic, Schories, Christoph, Groga-Bada, Patrick, Martus, Peter, Borst, Oliver, Gawaz, Meinrad, Geisler, Tobias, Rath, Dominik, Chatterjee, Madhumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570123/
https://www.ncbi.nlm.nih.gov/pubmed/36232370
http://dx.doi.org/10.3390/ijms231911066