The Autism Spectrum Disorder-Associated Bacterial Metabolite p-Cresol Derails the Neuroimmune Response of Microglial Cells Partially via Reduction of ADAM17 and ADAM10

The bacterial metabolite 4-methylphenol (para-cresol or p-cresol) and its derivative p-cresyl sulfate (pCS) are elevated in the urine and feces of children with autism spectrum disorder (ASD). It has been shown that p-cresol administration induces social behavior deficits and repetitive behavior in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Yuanpeng, Prince, Naika Z., Peralta Marzal, Lucia N., Ahmed, Sabbir, Garssen, Johan, Perez Pardo, Paula, Kraneveld, Aletta D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570133/
https://www.ncbi.nlm.nih.gov/pubmed/36232346
http://dx.doi.org/10.3390/ijms231911013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570133/
https://www.ncbi.nlm.nih.gov/pubmed/36232346
http://dx.doi.org/10.3390/ijms231911013

Ejemplares similares