PINK1 Phosphorylates Drp1(S616) to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF

(1) Background: Heart failure with preserved ejection fraction (HFpEF) is a major subtype of HF with no effective treatments. Mitochondrial dysfunctions relevant to the imbalance of fusion and fission occur in HFpEF. Drp1 is a key protein regulating mitochondrial fission, and PINK1 is the upstream a...

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Detalles Bibliográficos
Autores principales: Shou, Jian, Huo, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570161/
https://www.ncbi.nlm.nih.gov/pubmed/36233236
http://dx.doi.org/10.3390/ijms231911934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570161/
https://www.ncbi.nlm.nih.gov/pubmed/36233236
http://dx.doi.org/10.3390/ijms231911934

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