Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress

Herein, we report that chromone-containing allylmorpholines can affect ion channels formed by pore-forming antibiotics in model lipid membranes, which correlates with their ability to influence membrane boundary potential and lipid-packing stress. At 100 µg/mL, allylmorpholines 1, 6, 7, and 8 decrea...

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Detalles Bibliográficos
Autores principales: Efimova, Svetlana S., Martynyuk, Vera A., Zakharova, Anastasiia A., Yudintceva, Natalia M., Chernov, Nikita M., Yakovlev, Igor P., Ostroumova, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570167/
https://www.ncbi.nlm.nih.gov/pubmed/36232854
http://dx.doi.org/10.3390/ijms231911554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570167/
https://www.ncbi.nlm.nih.gov/pubmed/36232854
http://dx.doi.org/10.3390/ijms231911554

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