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Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress
Herein, we report that chromone-containing allylmorpholines can affect ion channels formed by pore-forming antibiotics in model lipid membranes, which correlates with their ability to influence membrane boundary potential and lipid-packing stress. At 100 µg/mL, allylmorpholines 1, 6, 7, and 8 decrea...
Autores principales: | Efimova, Svetlana S., Martynyuk, Vera A., Zakharova, Anastasiia A., Yudintceva, Natalia M., Chernov, Nikita M., Yakovlev, Igor P., Ostroumova, Olga S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570167/ https://www.ncbi.nlm.nih.gov/pubmed/36232854 http://dx.doi.org/10.3390/ijms231911554 |
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