Improved HPLC Quantification of 6-Mercaptopurine Metabolites in Red Blood Cells: Monitoring Data and Literature Analysis

Thiopurine drugs azathioprine (AZA) and 6-mercaptopurine (6-MP) are used extensively in pediatric and adult patients with inflammatory and neoplastic diseases. They are metabolized to 6-thioguanine nucleotides (6-TGN) or to 6-methyl-mercaptopurine nucleotides (6-MMPN). The balance between 6-TGN and...

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Detalles Bibliográficos
Autores principales: Adam de Beaumais, Tiphaine, Medard, Yves, Amblard, Océane, Goldwirt, Lauriane, Simonin, Mathieu, Martinez Vinson, Christine, Petit, Arnaud, Jacqz-Aigrain, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570176/
https://www.ncbi.nlm.nih.gov/pubmed/36233187
http://dx.doi.org/10.3390/ijms231911885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570176/
https://www.ncbi.nlm.nih.gov/pubmed/36233187
http://dx.doi.org/10.3390/ijms231911885

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