Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

Glutamate dehydrogenase (GDH) plays a key role in the metabolism of glutamate, an important compound at a cross-road of carbon and nitrogen metabolism and a relevant neurotransmitter. Despite being one of the first discovered allosteric enzymes, GDH still poses challenges for structural characteriza...

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Detalles Bibliográficos
Autores principales: Aleshin, Vasily A., Bunik, Victoria I., Bruch, Eduardo M., Bellinzoni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570180/
https://www.ncbi.nlm.nih.gov/pubmed/36232607
http://dx.doi.org/10.3390/ijms231911306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570180/
https://www.ncbi.nlm.nih.gov/pubmed/36232607
http://dx.doi.org/10.3390/ijms231911306

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