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Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

Glutamate dehydrogenase (GDH) plays a key role in the metabolism of glutamate, an important compound at a cross-road of carbon and nitrogen metabolism and a relevant neurotransmitter. Despite being one of the first discovered allosteric enzymes, GDH still poses challenges for structural characteriza...

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Detalles Bibliográficos
Autores principales:	Aleshin, Vasily A., Bunik, Victoria I., Bruch, Eduardo M., Bellinzoni, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570180/ https://www.ncbi.nlm.nih.gov/pubmed/36232607 http://dx.doi.org/10.3390/ijms231911306

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