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Selective Calpain Inhibition Improves Functional and Histopathological Outcomes in a Canine Spinal Cord Injury Model

Calpain activation has been implicated in various pathologies, including neurodegeneration. Thus, calpain inhibition could effectively prevent spinal cord injury (SCI) associated with neurodegeneration. In the current study, a dog SCI model was used to evaluate the therapeutic potential of a selecti...

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Detalles Bibliográficos
Autores principales: Metwally, Elsayed, Al-Abbadi, Hatim A., Hashem, Mohamed A., Mahmoud, Yasmina K., Ahmed, Eman A., Maaty, Ahmed I., Helal, Ibrahim E., Ahmed, Mahmoud F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570220/
https://www.ncbi.nlm.nih.gov/pubmed/36233068
http://dx.doi.org/10.3390/ijms231911772