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A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates

Despite advances in diagnostic and therapeutic approaches for lung cancer, new therapies targeting metastasis by the specific regulation of cancer genes are needed. In this study, we screened a small library of epigenetic inhibitors in non-small-cell lung cancer (NSCLC) cell lines and evaluated 38 e...

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Detalles Bibliográficos
Autores principales: Lesbon, Jéssika Cristina Chagas, Garnica, Taismara Kustro, Xavier, Pedro Luiz Porfírio, Rochetti, Arina Lázaro, Reis, Rui Manuel, Müller, Susanne, Fukumasu, Heidge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570250/
https://www.ncbi.nlm.nih.gov/pubmed/36233212
http://dx.doi.org/10.3390/ijms231911911