Tracking Topological and Electronic Effects on the Folding and Stability of Guanine-Deficient RNA G-Quadruplexes, Engineered with a New Computational Tool for De Novo Quadruplex Folding

The initial aim of this work was to elucidate the mutual influence of different single-stranded segments (loops and caps) on the thermodynamic stability of RNA G-quadruplexes. To this end, we used a new NAB-GQ-builder software program, to construct dozens of two-tetrad G-quadruplex topologies, based...

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Detalles Bibliográficos
Autores principales: Göç, Yavuz Burak, Poziemski, Jakub, Smolińska, Weronika, Suwała, Dominik, Wieczorek, Grzegorz, Niedzialek, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570295/
https://www.ncbi.nlm.nih.gov/pubmed/36232294
http://dx.doi.org/10.3390/ijms231910990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570295/
https://www.ncbi.nlm.nih.gov/pubmed/36232294
http://dx.doi.org/10.3390/ijms231910990

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