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Docking and Molecular Dynamics-Based Identification of Interaction between Various Beta-Amyloid Isoforms and RAGE Receptor

Beta-amyloid peptide (Aβ) is a ligand associated with RAGE (Advanced glycosylation end product-specific receptor). Aβ is translocated in complexes with RAGE from the blood to brain across the blood–brain barrier (BBB) by transcytosis. Aβ and its isoforms are important factors in the Alzheimer’s dise...

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Detalles Bibliográficos
Autores principales: Tolstova, Anna P., Adzhubei, Alexei A., Mitkevich, Vladimir A., Petrushanko, Irina Yu., Makarov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570301/
https://www.ncbi.nlm.nih.gov/pubmed/36233130
http://dx.doi.org/10.3390/ijms231911816