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Docking and Molecular Dynamics-Based Identification of Interaction between Various Beta-Amyloid Isoforms and RAGE Receptor
Beta-amyloid peptide (Aβ) is a ligand associated with RAGE (Advanced glycosylation end product-specific receptor). Aβ is translocated in complexes with RAGE from the blood to brain across the blood–brain barrier (BBB) by transcytosis. Aβ and its isoforms are important factors in the Alzheimer’s dise...
Autores principales: | Tolstova, Anna P., Adzhubei, Alexei A., Mitkevich, Vladimir A., Petrushanko, Irina Yu., Makarov, Alexander A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570301/ https://www.ncbi.nlm.nih.gov/pubmed/36233130 http://dx.doi.org/10.3390/ijms231911816 |
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