MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases

MOTS-c, a 16 amino acid mitochondrial derived peptide, is encoded from the 12S rRNA region of the mitochondrial genome. Under stress conditions, MOTS-c translocates to the nucleus where it regulates a wide range of genes in response to metabolic dysfunction. It is colocalized to mitochondria in vari...

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Detalles Bibliográficos
Autores principales: Mohtashami, Zahra, Singh, Mithalesh K., Salimiaghdam, Nasim, Ozgul, Mustafa, Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570330/
https://www.ncbi.nlm.nih.gov/pubmed/36233287
http://dx.doi.org/10.3390/ijms231911991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570330/
https://www.ncbi.nlm.nih.gov/pubmed/36233287
http://dx.doi.org/10.3390/ijms231911991

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