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Allyl-, Butyl- and Phenylethyl-Isothiocyanate Modulate Akt–mTOR and Cyclin–CDK Signaling in Gemcitabine- and Cisplatin-Resistant Bladder Cancer Cell Lines

Combined cisplatin–gemcitabine treatment causes rapid resistance development in patients with advanced urothelial carcinoma. The present study investigated the potential of the natural isothiocyanates (ITCs) allyl-isothiocyanate (AITC), butyl-isothiocyanate (BITC), and phenylethyl-isothiocyanate (PE...

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Detalles Bibliográficos
Autores principales: Rutz, Jochen, Maxeiner, Sebastian, Grein, Timothy, Sonnenburg, Marlon, Khadir, Salma El, Makhatelashvili, Nino, Mann, Johanna, Xie, Hui, Cinatl, Jindrich, Thomas, Anita, Chun, Felix K.-H., Haferkamp, Axel, Blaheta, Roman A., Tsaur, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570347/
https://www.ncbi.nlm.nih.gov/pubmed/36232303
http://dx.doi.org/10.3390/ijms231910996