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Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia

Background: Hyperammonemia is a main contributor to minimal hepatic encephalopathy (MHE) in cirrhotic patients. Hyperammonemic rats reproduce the motor incoordination of MHE patients, which is due to enhanced GABAergic neurotransmission in the cerebellum as a consequence of neuroinflammation. In hyp...

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Detalles Bibliográficos
Autores principales: Arenas, Yaiza M., Martínez-García, Mar, Llansola, Marta, Felipo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570361/
https://www.ncbi.nlm.nih.gov/pubmed/36233065
http://dx.doi.org/10.3390/ijms231911770