Decreased Prosaposin and Progranulin in the Cingulate Cortex Are Associated with Schizophrenia Pathophysiology

Prosaposin (PSAP) and progranulin (PGRN) are two lysosomal proteins that interact and modulate the metabolism of lipids, particularly sphingolipids. Alterations in sphingolipid metabolism have been found in schizophrenia. Genetic associations of PSAP and PGRN with schizophrenia have been reported. T...

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Detalles Bibliográficos
Autores principales: He, Yachao, Zhang, Xiaoqun, Flais, Ivana, Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570388/
https://www.ncbi.nlm.nih.gov/pubmed/36233357
http://dx.doi.org/10.3390/ijms231912056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570388/
https://www.ncbi.nlm.nih.gov/pubmed/36233357
http://dx.doi.org/10.3390/ijms231912056

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