Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease

Kidneys play an especial role in copper redistribution in the organism. The epithelial cells of proximal tubules perform the functions of both copper uptake from the primary urine and release to the blood. These cells are equipped on their apical and basal membrane with copper transporters CTR1 and...

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Detalles Bibliográficos
Autores principales: Haberkiewicz, Olga, Lipiński, Paweł, Starzyński, Rafał R., Jończy, Aneta, Kurowska, Patrycja, Ogórek, Mateusz, Bednarz, Aleksandra, Herman, Sylwia, Hatala, Dawid, Grzmil, Paweł, Rajfur, Zenon, Baster, Zbigniew, Lenartowicz, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570402/
https://www.ncbi.nlm.nih.gov/pubmed/36232742
http://dx.doi.org/10.3390/ijms231911441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570402/
https://www.ncbi.nlm.nih.gov/pubmed/36232742
http://dx.doi.org/10.3390/ijms231911441

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