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Iron Deposition and Ferroptosis in the Spleen in a Murine Model of Acute Radiation Syndrome

Total body irradiation (TBI) can result in death associated with hematopoietic insufficiency. Although radiation causes apoptosis of white blood cells, red blood cells (RBC) undergo hemolysis due to hemoglobin denaturation. RBC lysis post-irradiation results in the release of iron into the plasma, p...

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Detalles Bibliográficos
Autores principales: Rittase, W. Bradley, Slaven, John E., Suzuki, Yuichiro J., Muir, Jeannie M., Lee, Sang-Ho, Rusnak, Milan, Brehm, Grace V., Bradfield, Dmitry T., Symes, Aviva J., Day, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570444/
https://www.ncbi.nlm.nih.gov/pubmed/36232330
http://dx.doi.org/10.3390/ijms231911029