Unveiling Targets for Treating Postoperative Pain: The Role of the TNF-α/p38 MAPK/NF-κB/Nav1.8 and Nav1.9 Pathways in the Mouse Model of Incisional Pain

Although the mouse model of incisional pain is broadly used, the mechanisms underlying plantar incision-induced nociception are not fully understood. This work investigates the role of Na(v)1.8 and Na(v)1.9 sodium channels in nociceptive sensitization following plantar incision in mice and the signa...

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Detalles Bibliográficos
Autores principales: de Lima, Flávia Oliveira, Lauria, Pedro Santana Sales, do Espírito-Santo, Renan Fernandes, Evangelista, Afrânio Ferreira, Nogueira, Tâmara Magalhães Oliveira, Araldi, Dionéia, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570460/
https://www.ncbi.nlm.nih.gov/pubmed/36232927
http://dx.doi.org/10.3390/ijms231911630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570460/
https://www.ncbi.nlm.nih.gov/pubmed/36232927
http://dx.doi.org/10.3390/ijms231911630

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