Cargando…
The Hydrophobic Residues in Amino Terminal Domains of Cx46 and Cx50 Are Important for Their Gap Junction Channel Ion Permeation and Gating
Lens gap junctions (GJs) formed by Cx46 and Cx50 are important to keep lens transparency. Functional studies on Cx46 and Cx50 GJs showed that the V(j)-gating, single channel conductance (γ(j)), gating polarity, and/or channel open stability could be modified by the charged residues in the amino term...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570504/ https://www.ncbi.nlm.nih.gov/pubmed/36232905 http://dx.doi.org/10.3390/ijms231911605 |