Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives

Sirtuin 1 (SIRT1) is a NAD(+)-dependent deacetylase implicated in various biological and pathological processes, including cancer, diabetes, and cardiovascular diseases. In recent years, SIRT1-activating compounds have been demonstrated to exert cardioprotective effects. Therefore, this enzyme has b...

Descripción completa

Detalles Bibliográficos
Autores principales: Bononi, Giulia, Citi, Valentina, Lapillo, Margherita, Martelli, Alma, Poli, Giulio, Tuccinardi, Tiziano, Granchi, Carlotta, Testai, Lara, Calderone, Vincenzo, Minutolo, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570679/
https://www.ncbi.nlm.nih.gov/pubmed/36235072
http://dx.doi.org/10.3390/molecules27196535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570679/
https://www.ncbi.nlm.nih.gov/pubmed/36235072
http://dx.doi.org/10.3390/molecules27196535

Ejemplares similares