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Using the Cyclotide Scaffold for Targeting Biomolecular Interactions in Drug Development

This review provides an overview of the properties of cyclotides and their potential for developing novel peptide-based therapeutics. The selective disruption of protein–protein interactions remains challenging, as the interacting surfaces are relatively large and flat. However, highly constrained p...

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Detalles Bibliográficos
Autores principales: Jacob, Binu, Vogelaar, Alicia, Cadenas, Enrique, Camarero, Julio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570680/
https://www.ncbi.nlm.nih.gov/pubmed/36234971
http://dx.doi.org/10.3390/molecules27196430