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Synthesis and Inhibitory Activity of Machaeridiol-Based Novel Anti-MRSA and Anti-VRE Compounds and Their Profiling for Cancer-Related Signaling Pathways

Three unique 5,6-seco-hexahydrodibenzopyrans (seco-HHDBP) machaeridiols A–C, reported previously from Machaerium Pers., have displayed potent activities against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium, and E. faecalis (VRE). In order to enrich th...

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Detalles Bibliográficos
Autores principales: Kumarihamy, Mallika, Tripathi, Siddharth, Balachandran, Premalatha, Avula, Bharathi, Zhao, Jianping, Wang, Mei, Bennett, Maria M., Zhang, Jin, Carr, Mary A., Lovell, K. Michael, Wellington, Ocean I., Marquart, Mary E., Nanayakkara, N. P. Dhammika, Muhammad, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570708/
https://www.ncbi.nlm.nih.gov/pubmed/36235141
http://dx.doi.org/10.3390/molecules27196604