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Effects of a Shift of the Signal Peptide Cleavage Site in Signal Peptide Variant on the Synthesis and Secretion of SARS-CoV-2 Spike Protein

The COVID-19 pandemic is caused by SARS-CoV-2; the spike protein is a key structural protein that mediates infection of the host by SARS-CoV-2. In this study, we aimed to evaluate the effects of signal peptide on the secretion and release of SARS-CoV-2 spike protein. Therefore, we constructed a sign...

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Detalles Bibliográficos
Autores principales: Zhang, Zhikai, Wan, Xuan, Li, Xinyue, Wan, Chengsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570739/
https://www.ncbi.nlm.nih.gov/pubmed/36235223
http://dx.doi.org/10.3390/molecules27196688