Conformational Essentials Responsible for Neurotoxicity of Aβ42 Aggregates Revealed by Antibodies against Oligomeric Aβ42

Soluble aggregation of amyloid β-peptide 1-42 (Aβ42) and deposition of Aβ42 aggregates are the initial pathological hallmarks of Alzheimer’s disease (AD). The bipolar nature of Aβ42 molecule results in its ability to assemble into distinct oligomers and higher aggregates, which may drive some of the...

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Detalles Bibliográficos
Autores principales: Song, Chuli, Zhang, Tianyu, Zhang, Yingjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570743/
https://www.ncbi.nlm.nih.gov/pubmed/36235284
http://dx.doi.org/10.3390/molecules27196751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570743/
https://www.ncbi.nlm.nih.gov/pubmed/36235284
http://dx.doi.org/10.3390/molecules27196751

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