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Design, Synthesis, and Biological Evaluation of Novel Dihydropyridine and Pyridine Analogs as Potent Human Tissue Nonspecific Alkaline Phosphatase Inhibitors with Anticancer Activity: ROS and DNA Damage-Induced Apoptosis

Small molecules with nitrogen-containing scaffolds have gained much attention due to their biological importance in the development of new anticancer agents. The present paper reports the synthesis of a library of new dihydropyridine and pyridine analogs with diverse pharmacophores. All compounds we...

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Detalles Bibliográficos
Autores principales: Khan, Nazeer Ahmad, Rashid, Faisal, Jadoon, Muhammad Siraj Khan, Jalil, Saquib, Khan, Zulfiqar Ali, Orfali, Raha, Perveen, Shagufta, Al-Taweel, Areej, Iqbal, Jamshed, Shahzad, Sohail Anjum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570995/
https://www.ncbi.nlm.nih.gov/pubmed/36234774
http://dx.doi.org/10.3390/molecules27196235