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Chemoenzymatic Synthesis of Select Intermediates and Natural Products of the Desferrioxamine E Siderophore Pathway

The NIS synthetase family of enzymes responsible for the biosynthesis of siderophores is increasingly associated with bacterial virulence. Proteins in this class represent outstanding potential drug targets, assuming that basic biochemical and structural characterizations can be completed. Towards t...

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Detalles Bibliográficos
Autores principales: Hoffmann, Katherine M., Kingsbury, Jason S., March, Nathan L., Jang, Yoojin, Nguyen, James H., Hutt, Miranda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571020/
https://www.ncbi.nlm.nih.gov/pubmed/36234688
http://dx.doi.org/10.3390/molecules27196144