ABCB1 Is Frequently Methylated in Higher-Grade Gliomas and May Serve as a Diagnostic Biomarker of More Aggressive Tumors

ABCB1 belongs to a superfamily of membrane transporters that use ATP hydrolysis to efflux various endogenous compounds and drugs outside the cell. Cancer cells upregulate ABCB1 expression as an adaptive response to evade chemotherapy-mediated cell death. On the other hand, several reports highlight...

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Detalles Bibliográficos
Autores principales: Majchrzak-Celińska, Aleksandra, Sidhu, Arvinder, Miechowicz, Izabela, Nowak, Witold, Barciszewska, Anna-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571128/
https://www.ncbi.nlm.nih.gov/pubmed/36233525
http://dx.doi.org/10.3390/jcm11195655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571128/
https://www.ncbi.nlm.nih.gov/pubmed/36233525
http://dx.doi.org/10.3390/jcm11195655

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