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Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology and Gut Microbiota

Forty compounds were isolated and characterized from A. tenuissimum flower. Among them, twelve flavonoids showed higher α−glucosidase inhibition activities in vitro than acarbose, especially kaempferol. The molecular docking results showed that the binding of kaempferol to α−glucosidase (GAA) could...

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Detalles Bibliográficos
Autores principales: Zhang, Shan-Shan, Hou, Yu-Fei, Liu, Shao-Jing, Guo, Sen, Ho, Chi-Tang, Bai, Nai-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571170/
https://www.ncbi.nlm.nih.gov/pubmed/36235633
http://dx.doi.org/10.3390/nu14193980