Site-Specific Radioiodination of Oligonucleotides with a Phenolic Element in a Programmable Approach

Radioiodination of oligonucleotides provides an extra modality for nucleic acid-based theranostics with potential applications. Herein, we report the design and synthesis of a phosphoramidite embedded with a phenolic moiety and demonstrate that oligonucleotides can be readily functionalized with phe...

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Detalles Bibliográficos
Autores principales: Zhao, Haitao, Qin, Yu, Liu, Dunfang, Geng, Xinyao, Wang, Cheng, Ding, Ding, Ding, Xuan, Xia, Qian, Liu, Jianjun, Wang, Ruowen, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571250/
https://www.ncbi.nlm.nih.gov/pubmed/36234794
http://dx.doi.org/10.3390/molecules27196257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571250/
https://www.ncbi.nlm.nih.gov/pubmed/36234794
http://dx.doi.org/10.3390/molecules27196257

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