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The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents

A series of novel aloe-emodin–coumarin hybrids were designed and synthesized. The antitumor activity of these derivatives was evaluated against five human tumor cell lines (A549, SGC-7901, HepG2, MCF-7 and HCT-8). Some of the synthesized compounds exhibited moderate to good activity against one or m...

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Detalles Bibliográficos
Autores principales: Shang, Hai, Hu, Yue, Li, Jingrong, Li, Lingyu, Tian, Yu, Li, Xiaoxue, Wu, Qi, Zou, Zhongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571363/
https://www.ncbi.nlm.nih.gov/pubmed/36234685
http://dx.doi.org/10.3390/molecules27196153