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The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents
A series of novel aloe-emodin–coumarin hybrids were designed and synthesized. The antitumor activity of these derivatives was evaluated against five human tumor cell lines (A549, SGC-7901, HepG2, MCF-7 and HCT-8). Some of the synthesized compounds exhibited moderate to good activity against one or m...
Autores principales: | Shang, Hai, Hu, Yue, Li, Jingrong, Li, Lingyu, Tian, Yu, Li, Xiaoxue, Wu, Qi, Zou, Zhongmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571363/ https://www.ncbi.nlm.nih.gov/pubmed/36234685 http://dx.doi.org/10.3390/molecules27196153 |
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