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ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway

BACKGROUND: Apart from the current understanding of enzyme function, the mechanism of ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1) deficiency-associated osteoporosis is unknown. We aimed to explore the changes in the expression of signaling pathways of bone tissues involved in Enpp1 de...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Gao, Zhiqiang, Guo, Kai, Lu, Jiawei, Wang, Feng, Huang, Yufeng, Wu, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571425/
https://www.ncbi.nlm.nih.gov/pubmed/36243801
http://dx.doi.org/10.1186/s13018-022-03349-1