Design, Synthesis, Anti-Varicella-Zoster and Antimicrobial Activity of (Isoxazolidin-3-yl)Phosphonate Conjugates of N1-Functionalised Quinazoline-2,4-Diones

Dipolar cycloaddition of the N-substituted C-(diethoxyphosphonyl)nitrones with N(3)-allyl-N(1)-benzylquinazoline-2,4-diones produced mixtures of diastereoisomeric 3-(diethoxyphosphonyl)isoxazolidines with a N(1)-benzylquinazoline-2,4-dione unit at C5. The obtained compounds were assessed for antivir...

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Detalles Bibliográficos
Autores principales: Łysakowska, Magdalena, Głowacka, Iwona E., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Lisiecki, Paweł, Szemraj, Magdalena, Piotrowska, Dorota G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571433/
https://www.ncbi.nlm.nih.gov/pubmed/36235061
http://dx.doi.org/10.3390/molecules27196526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571433/
https://www.ncbi.nlm.nih.gov/pubmed/36235061
http://dx.doi.org/10.3390/molecules27196526

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