Identification of acetic acid sensitive strains through biosensor-based screening of a Saccharomyces cerevisiae CRISPRi library

BACKGROUND: Acetic acid tolerance is crucial for the development of robust cell factories for conversion of lignocellulosic hydrolysates that typically contain high levels of acetic acid. Screening mutants for growth in medium with acetic acid is an attractive way to identify sensitive variants and...

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Detalles Bibliográficos
Autores principales: Mormino, Maurizio, Lenitz, Ibai, Siewers, Verena, Nygård, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571444/
https://www.ncbi.nlm.nih.gov/pubmed/36243715
http://dx.doi.org/10.1186/s12934-022-01938-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571444/
https://www.ncbi.nlm.nih.gov/pubmed/36243715
http://dx.doi.org/10.1186/s12934-022-01938-7

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