Exosomal miR-140-5p inhibits osteogenesis by targeting IGF1R and regulating the mTOR pathway in ossification of the posterior longitudinal ligament

BACKGROUND: Ossification of the posterior longitudinal ligament (OPLL) is a disabling disease whose pathogenesis is still unclear, and there are no effective cures or prevention methods. Exosomal miRNA plays an important role in the osteogenesis of ectopic bone. Therefore, we focused on the downregu...

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Detalles Bibliográficos
Autores principales: Tang, Yifan, Sun, Yanqing, Zeng, Junkai, Yuan, Bo, Zhao, Yin, Geng, Xiangwu, Jia, Lianshun, Zhou, Shengyuan, Chen, Xiongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571456/
https://www.ncbi.nlm.nih.gov/pubmed/36243800
http://dx.doi.org/10.1186/s12951-022-01655-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571456/
https://www.ncbi.nlm.nih.gov/pubmed/36243800
http://dx.doi.org/10.1186/s12951-022-01655-8

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