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Antitumor activity of the protein kinase inhibitor 1-(β-D-2′-deoxyribofuranosyl)-4,5,6,7-tetrabromo- 1H-benzimidazole in breast cancer cell lines

BACKGROUND: The protein kinases CK2 and PIM-1 are involved in cell proliferation and survival, the cell cycle, and drug resistance, and they are found overexpressed in virtually all types of human cancer, including breast cancer. In this study, we investigated the antitumor activity of a deoxynucleo...

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Detalles Bibliográficos
Autores principales: Koronkiewicz, Mirosława, Kazimierczuk, Zygmunt, Orzeszko, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571492/
https://www.ncbi.nlm.nih.gov/pubmed/36243702
http://dx.doi.org/10.1186/s12885-022-10156-8