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Antitumor activity of the protein kinase inhibitor 1-(β-D-2′-deoxyribofuranosyl)-4,5,6,7-tetrabromo- 1H-benzimidazole in breast cancer cell lines
BACKGROUND: The protein kinases CK2 and PIM-1 are involved in cell proliferation and survival, the cell cycle, and drug resistance, and they are found overexpressed in virtually all types of human cancer, including breast cancer. In this study, we investigated the antitumor activity of a deoxynucleo...
Autores principales: | Koronkiewicz, Mirosława, Kazimierczuk, Zygmunt, Orzeszko, Andrzej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571492/ https://www.ncbi.nlm.nih.gov/pubmed/36243702 http://dx.doi.org/10.1186/s12885-022-10156-8 |
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