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Transcriptomes of Clusterin- and S100B-transfected neuronal cells elucidate protective mechanisms against hypoxia and oxidative stress in the hooded seal (Cystophora cristata) brain

BACKGROUND: The hooded seal (Cystophora cristata) exhibits impressive diving skills and can tolerate extended durations of asphyxia, hypoxia and oxidative stress, without suffering from irreversible neuronal damage. Thus, when exposed to hypoxia in vitro, neurons of fresh cortical and hippocampal ti...

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Detalles Bibliográficos
Autores principales: Martens, Gerrit A., Geßner, Cornelia, Osterhof, Carina, Hankeln, Thomas, Burmester, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571494/
https://www.ncbi.nlm.nih.gov/pubmed/36243678
http://dx.doi.org/10.1186/s12868-022-00744-6