Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice

Research has connected Parkinson’s disease (PD) with impaired intestinal barrier. The activation of G-protein-coupled receptor 109A (GPR109A) protects the intestinal barrier by inhibiting the NF-κB signaling pathway. Sodium butyrate (NaB), which is a GPR109A ligand, may have anti-PD effects. The cur...

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Detalles Bibliográficos
Autores principales: Xu, Rui-Chen, Miao, Wen-Teng, Xu, Jing-Yi, Xu, Wen-Xin, Liu, Ming-Ran, Ding, Song-Tao, Jian, Yu-Xin, Lei, Yi-Han, Yan, Ning, Liu, Han-Deng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571500/
https://www.ncbi.nlm.nih.gov/pubmed/36235813
http://dx.doi.org/10.3390/nu14194163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571500/
https://www.ncbi.nlm.nih.gov/pubmed/36235813
http://dx.doi.org/10.3390/nu14194163

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