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New Triazinoindole Bearing Benzimidazole/Benzoxazole Hybrids Analogs as Potent Inhibitors of Urease: Synthesis, In Vitro Analysis and Molecular Docking Studies

Twenty-four analogs based on triazinoindole bearing benzimidazole/benzoxazole moieties (1–25) were synthesized. Utilizing a variety of spectroscopic methods, including (1)H-, (13)C-NMR, and HREI-MS, the newly afforded compounds (1–25) were analyzed. The synthesized analogs were tested against urease...

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Detalles Bibliográficos
Autores principales: Mumtaz, Sundas, Iqbal, Shahid, Shah, Mazloom, Hussain, Rafaqat, Rahim, Fazal, Rehman, Wajid, Khan, Shoaib, Abid, Obaid-ur-Rahman, Rasheed, Liaqat, Dera, Ayed A., Al-ghulikah, Hanan A., Kehili, Sana, Elkaeed, Eslam B., Alrbyawi, Hamad, Alahmdi, Mohammed Issa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571547/
https://www.ncbi.nlm.nih.gov/pubmed/36235116
http://dx.doi.org/10.3390/molecules27196580