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Decreased Tertiary Lymphoid Structures in Lung Adenocarcinomas with ALK Rearrangements

Purpose: This study sought to characterize the tumor immune microenvironment (TIME) of lung adenocarcinomas with ALK rearrangements (ALK+ LUAD), which responds poorly to immune checkpoint inhibitors (ICIs) therapy. Materials and methods: Immune score evaluation and immunohistochemical (IHC) validati...

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Detalles Bibliográficos
Autores principales: Zou, Yi, Zhao, Jing, Huang, Fengbo, Xiang, Xueping, Xia, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572246/
https://www.ncbi.nlm.nih.gov/pubmed/36233802
http://dx.doi.org/10.3390/jcm11195935