Effect of Hydrophilic Polymers on the Release Rate and Pharmacokinetics of Acyclovir Tablets Obtained by Wet Granulation: In Vitro and In Vivo Assays

This study aims to evaluate the feasibility of producing acyclovir-containing modified release matrix tablets by a wet granulation method based on the type and concentration of two pharmaceutical-grade hydrophilic matrix polymers (i.e., hydroxypropyl methylcellulose (HPMC), carbomers, and their comb...

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Detalles Bibliográficos
Autores principales: Venkatesh, D. Nagasamy, Meyyanathan, Subramanianainar N., Kovacevic, Andjelka, Zielińska, Aleksandra, Fonseca, Joel, Eder, Piotr, Dobrowolska, Agnieszka, Souto, Eliana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572380/
https://www.ncbi.nlm.nih.gov/pubmed/36235026
http://dx.doi.org/10.3390/molecules27196490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572380/
https://www.ncbi.nlm.nih.gov/pubmed/36235026
http://dx.doi.org/10.3390/molecules27196490

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