Enzalutamide Induces Apoptotic Insults to Human Drug-Resistant and -Sensitive Glioblastoma Cells via an Intrinsic Bax-Mitochondrion-Cytochrome C Caspase Cascade Activation Pathway

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor. Temozolomide (TMZ) is the first-line chemotherapeutic drug for treating GBM. However, drug resistance is still a challenging issue in GBM therapy. Our preliminary results showed upregulation of androgen receptor (AR) gene ex...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Yu, Chen, Jui-Tai, Chen, Tso-Hsiao, Chen, Ruei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572438/
https://www.ncbi.nlm.nih.gov/pubmed/36235203
http://dx.doi.org/10.3390/molecules27196666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9572438/
https://www.ncbi.nlm.nih.gov/pubmed/36235203
http://dx.doi.org/10.3390/molecules27196666

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